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Search Results for " protac bcl-2 degrader-1 "

4

Compounds

Cat No. Product Name Synonyms Targets
T10485 PROTAC Bcl2 degrader-1 BCL
PROTAC Bcl2 degrader-1 is a PROTAC, which potently and selectively induces the degradation of Mcl-1 (IC50: 11.81 μM) and Bcl-2 (IC50: 4.94 μM; DC50: 3.0 μM).
T39910 Desmorpholinyl Navitoclax-NH-Me Desmorpholinyl ABT-263-NH-Me,Desmorpholinyl Navitoclax-NH-Me BCL
Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a PROTAC BCL-XL degrader [1] [2].
T73957 PROTAC Bcl-xL degrader-1
PROTAC Bcl-xL degrader-1 is a potent PROTAC composed of a Bcl-xL (Bcl-2 family member) ligand-binding group, a linker, and an IAP E3 ligases binding group, demonstrating effectiveness as a Bcl-xL degrader. It exhibits to...
T73826 PZ703b hydrochloride
PZ703b hydrochloride, a Bcl-xl PROTAC degrader, effectively induces apoptosis and curbs the proliferation of cancer cells. It is primarily utilized in the study of bladder cancer [1] [2].
TargetMol